Recombinant Human CIB2, His-tagged

• Cat.No.: CIB2-3474H
• Product Overview: Recombinant human CIB2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: CIB2 belongs to calcium and integrin-binding family. CIB2 may be a Ca2+-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunit (DNA-PKcs). In skeletal muscle, CIB2 colocalizes with the integrin alpha7B subunit at the sarcolemma and at the neuromuscular and myotendinous junctions. CIB2 is closely related to CIB1.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 100mM NaCl, 1mM PMSF
• Molecular Weight: 23.8kDa (207aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
• Purity: > 90% by SDS - PAGE
• Concentration: 0.5mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGNKQTIFTE EQLDNYQDCT FFNKKDILKL HSRFYELAPN LVPMDYRKSP IVHVPMSLII QMPELRENPF KERIVAAFSE DGEGNLTFND FVDMFSVLCE SAPRELKANY AFKIYDFNTD NFICKEDLEL TLARLTKSEL DEEEVVLVCD KVIEEADLDG DGKLGFADFE DMIAKAPDFL STFHIRI
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CIB2 calcium and integrin binding family member 2 [ Homo sapiens ]
• Synonyms: CIB2; calcium and integrin binding family member 2; KIP2; 2810434I23Rik; DNA-dependent protein kinase catalytic subunit-interacting protein 2; kinase-interacting protein 2
• Gene ID: 10518
• mRNA Refseq: NM_006383
• Protein Refseq: NP_006374
• MIM: 605564
• UniProt ID: O75838
• Chromosome Location: 15q24
• Function: calcium ion binding