Recombinant Human Chromosome 6 Open Reading Frame 108, His-tagged

• Cat.No.: C6orf108-2808H
• Product Overview: Recombinant human RCL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 21.2 kDa (194aa), confirmed by MALDI-TOF.

Specification

• Cat. No.: C6orf108-2808H
• Description: Deoxyribonucleoside 5"-monophosphate N-glycosidase isoform 1, also known as RCL, belonged to the N-deoxyribosyltransferase family. This protein catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5"-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. RCL was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis.
• Source: E.coli.
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MAAAMVPGRS ESWERGEPGR PALYFCGSIR GGREDRTLYE RIVSRLRRFG TVLTEHVAAA ELGARGEEAA GGDRLIHEQD LEWLQQADVV VAEVTQPSLG VGYELGRAVA FNKRILCLFR PQSGRVLSAM IRGAADGSRF QVWDYEEGEV EALLDRYFEA DPPGQVAASP DPTT
• Purity: > 95% by SDS – PAGE.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: C6orf108 chromosome 6 open reading frame 108 [ Homo sapiens ]
• Synonyms: C6orf108; chromosome 6 open reading frame 108; RCL; dJ330M21.3; RP3-330M21.3; deoxyribonucleoside 5"-monophosphate N-glycosidase; OTTHUMP00000217077; putative c-Myc-responsive; c-Myc-responsive protein Rcl; EC 3.2.2.-
• Gene ID: 10591
• mRNA Refseq: NM_006443
• Protein Refseq: NP_006434
• UniProt ID: O43598
• Chromosome Location: 6p21.1
• Function: deoxyribonucleoside 5"-monophosphate N-glycosidase activity; hydrolase activity, acting on glycosyl bonds