Recombinant Human Chromosome 16 Open Reading Frame 53, His-tagged

• Cat.No.: C16orf53-1676H
• Product Overview: Recombinant human C16orf53protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: C16orf53 is acomponent of a Set1-like multiprotein histone methyltransferase complex. Itinteracts with PAXIP1/PTIP; the interaction is direct and is required for theassociation with the rest of the PTIP complex. This protein plays a criticalrole in maintaining genome stability, condensation of chromatin andprogression through mitosis.
• Concentration: 1 mg/ml
• Form: Supplied as a liquidin 20 mM Tris-HCl buffer, pH 8.0, containing 10% glycerol, 2 mM DTT and 0.1 MNaCl.
• Purity: > 85% pure bySDS-PAGE
• Sequence: 1-254 amino acids:MGSSHHHHHH SSGLVPRGSH MSLARGHGDT AASTAAPLSE EGEVTSGLQA LAVEDTGGPS ASAGKAEDEGEGGREETERE GSGGEEAQGE VPSAGGEEPA EEDSEDWCVP CSDEEVELPA DGQPWMPPPS EIQRLYELLAAHGTLELQAE ILPRRPPTPE AQSEEERSDE EPEAKEEEEE KPHMPTEFDF DDEPVTPKDS LIDRRRTPGSSARSQ
• Molecular Mass: 29.9 kDa (274 aa),confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
• Applications: SDS-PAGE
• Storage: C16orf53 proteinhas been used in SDS PAGE and may be suitable for use in other assays to bedetermined by the end user.
• OfficialSymbol: C16orf53

Gene Information

• Gene Name: C16orf53 chromosome 16 openreading frame 53 [ Homo sapiens ]
• Synonyms: C16orf53; chromosome16 open reading frame 53; GAS; PA1; MGC4606; FLJ22459;PAXIP1-associated protein 1; OTTHUMP00000162997; PTIP-associated 1 protein;PTIP-associated protein 1; glutamate-rich coactivator interacting withSRC1/NCOA1
• Gene ID: 79447
• mRNA Refseq: NM_024516
• Protein Refseq: NP_078792
• MIM: 612033
• UniProt ID: Q9BTK6
• Chromosome Location: 16p11.2
• Function: protein binding