Recombinant Human CHMP3 Protein, MYC/DDK-tagged

• Cat.No.: CHMP3-3234H
• Product Overview: Recombinant Human CHMP3 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 24.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CHMP3 charged multivesicular body protein 3 [ Homo sapiens ]
• Official Symbol: CHMP3
• Synonyms: CGI-149; NEDF; VPS24
• Gene ID: 51652
• mRNA Refseq: NM_016079.3
• Protein Refseq: NP_057163.1
• MIM: 610052
• UniProt ID: Q9Y3E7