Recombinant Human chemokine (C-C motif) ligand 5, His-tagged

• Cat.No.: CCL5-61H
• Product Overview: Recombinant Human CCL5 comprises a 68 amino acid fragment (24-91) corresponding to the mature RANTES protein and is expressed in E. coli with an amino-terminal hexahistidine tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 24-91 a.a.
• Description: CCL5 (acronym for Regulated upon Activation, Normal T-cell Expressed, and presumably Secreted) is a member of the beta (CC) chemokine subfamily and is predominantly produced from T cells and platelets. RANTES has been shown to be a chemoattractant factor for monocytes, CD4+/CD45RO+ T lymphocytes and basophils. It has also been shown to induce the proliferation and activation of killer cells and may act as a HIV suppressive factor.
• Purity: >95% by SDS-PAGE
• Form: Liquid
• Storage: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Gene Information

• Gene Name: CCL5 chemokine (C-C motif) ligand 5 [ Homo sapiens ]
• Synonyms: CCL5; D17S136E; MGC17164; RANTES; SCYA5; SISd; TCP228; chemokine (C-C motif) ligand 5; small inducible cytokine A5; SIS-delta; beta-chemokine RANTES; T-cell specific protein p288; T-cell specific RANTES protein; small inducible cytokine A5 (RANTES); small inducible cytokine subfamily A (Cys-Cys), member 5; regulated upon activation, normally T-expressed, and presumably secreted; CCL5; Chemokine (C-C motif) ligand 5; T-cell specific RANTES protein; T-cell; specific protein P288; beta chemokine RANTES precursor; SIS delta; EoCP; Eosinophil-chemotactic cytokine; T-cell specific RANTES protein; T-cell-specific protein RANTES; small inducible cytokine A5.
• Gene ID: 6352
• mRNA Refseq: NM_002985
• Protein Refseq: NP_002976
• MIM: 187011
• UniProt ID: P13501
• Chromosome Location: 17q11.2-q12
• Pathway: Cytokine-cytokine receptor interaction; Epithelial cell signaling in Helicobacter pylori infection; Toll-like receptor signaling pathway; :Signaling by GPCR
• Function: chemoattractant activity; chemokine activity; signal transducer activity