Recombinant Human CES5A Protein, His&GST-tagged

• Cat.No.: CES5A-752H
• Product Overview: Recombinant Human CES5A Protein (His383-Phe570) with His&GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They also participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene, also called CES5, is predominantly expressed in peripheral tissues, including brain, kidney, lung and testis. It encodes a secreted enzyme. Because of high levels in the urine of male domestic cats, this enzyme is also called cauxin (carboxylesterase-like urinary excreted protein). The enzyme functions in regulating the production of a pheromone precursor and may contribute to lipid and cholesterol transfer processes within male reproductive fluids. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 51.7 kDa; Accurate Molecular Mass: 54 kDa
• Protein length: His383-Phe570
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: CES5A carboxylesterase 5A [ Homo sapiens (human) ]
• Official Symbol: CES5A
• Synonyms: CES5A; carboxylesterase 5A; carboxylesterase 7, CES7; CAUXIN; CES4C1; CES5; FLJ31547; carboxylesterase 5; carboxylesterase 7; carboxylesterase-like urinary excreted protein homolog; CES7
• Gene ID: 221223
• mRNA Refseq: NM_145024
• Protein Refseq: NP_659461
• MIM: 618678
• UniProt ID: Q6NT32