Recombinant Human CES2 Protein, His-tagged

• Cat.No.: CES2-750H
• Product Overview: Recombinant Human CES2 Protein (Leu452-Leu623) with His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 24.1 kDa; Accurate Molecular Mass: 24 kDa
• Protein length: Leu452-Leu623
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: CES2 carboxylesterase 2 [ Homo sapiens (human) ]
• Official Symbol: CES2
• Synonyms: CES2; carboxylesterase 2; carboxylesterase 2 (intestine, liver); cocaine esterase; CE 2; CES2A1; iCE; hCE-2; methylumbelliferyl-acetate deacetylase 2; intestinal carboxylesterase; liver carboxylesterase-2; CE-2; PCE-2
• Gene ID: 8824
• mRNA Refseq: NM_003869
• Protein Refseq: NP_003860
• MIM: 605278
• UniProt ID: O00748