Recombinant Human CERS6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CERS6-1109H
• Product Overview: LASS6 MS Standard C13 and N15-labeled recombinant protein (NP_982288) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: CERS6 (Ceramide Synthase 6) is a Protein Coding gene. Diseases associated with CERS6 include Hereditary Sensory And Autonomic Neuropathy Type 1 and Aggressive Systemic Mastocytosis. Among its related pathways are Sphingolipid signaling pathway and Sphingolipid metabolism. Gene Ontology (GO) annotations related to this gene include sphingosine N-acyltransferase activity. An important paralog of this gene is CERS5.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 44.7 kDa
• AA Sequence: MAGILAWFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIALNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKPSTLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILELSFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLEAAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNLLLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSEPPGKNPHTATTTNGTSGTNGYLLTGSCSMDDTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CERS6 ceramide synthase 6 [ Homo sapiens (human) ]
• Official Symbol: CERS6
• Synonyms: CERS6; ceramide synthase 6; LAG1 homolog, ceramide synthase 6, LAG1 longevity assurance homolog 6 (S. cerevisiae), LASS6; longevity assurance homolog 6; LAG1 homolog, ceramide synthase 6; CERS5; LASS6; MGC129949; MGC129950; DKFZp434B102
• Gene ID: 253782
• mRNA Refseq: NM_203463
• Protein Refseq: NP_982288
• MIM: 615336
• UniProt ID: Q6ZMG9