Recombinant Human CEP27, His-tagged

• Cat.No.: CEP27-11111H
• Product Overview: Recombinant Human CEP27 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-235a.a.
• Description: HAUS2 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb augmentare, meaning to increase. The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: HAUS2 HAUS augmin-like complex, subunit 2 [ Homo sapiens ]
• Official Symbol: HAUS2
• Synonyms: HAUS2; HAUS augmin-like complex, subunit 2; C15orf25, centrosomal protein 27kDa , CEP27, chromosome 15 open reading frame 25; HAUS augmin-like complex subunit 2; FLJ10460; HsT17025; centrosomal protein 27kDa; centrosomal protein of 27 kDa; CEP27; C15orf25
• Gene ID: 55142
• mRNA Refseq: NM_001130447
• Protein Refseq: NP_001123919
• MIM: 613429
• UniProt ID: Q9NVX0
• Chromosome Location: 15q15.1
• Pathway: Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem; Loss of proteins required for interphase microtubule organization??from the centrosome, organism-specific biosystem; Mitotic G2-G2/M phases, organism-specific biosystem
• Function: molecular_function