Recombinant Human CEP110, His-tagged

• Cat.No.: CEP110-11106H
• Product Overview: Recombinant Human CEP110 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: C-term-331a.a.
• Description: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CENPL centromere protein L [ Homo sapiens ]
• Official Symbol: CNTRL
• Synonyms: CENP-L; C1orf155; dJ383J4.3; RP3-383J4.1; centromere protein L; interphase centromere complex protein 33; chromosome 1 open reading frame 155; dJ383J4.3; Interphase centromere complex protein 3
• Gene ID: 91687
• mRNA Refseq: NM_033319.3
• Protein Refseq: NP_201576.1
• MIM: 611503
• UniProt ID: Q8N0S6
• Chromosome Location: 1q25.1
• Function: Cell Cycle,organism-specific biosystem;Cell Cycle,Mitotic,organism-specific biosystem;DNA Replication,organism-specific biosystem;M Phase,organism-specific biosystem;Mitotic M-M/G1 phases,organism-specific biosystem;Mitotic Prometaphase,organism-specific