Recombinant Human CENPO Protein, GST-Tagged

• Cat.No.: CENPO-1123H
• Product Overview: Human CENPO full-length ORF (NP_077298.1, 1 a.a. - 300 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. Alternatively spliced transcript variants encoding multiple protein isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 60.2 kDa
• AA Sequence: MEQANPLRPDGESKGGVLAHLERLETQVSRSRKQSEELQSVQAQEGALGTKIHKLRRLRDELRAVVRHRRASVKACIANVEPNQTVEINEQEALEEKLENVKAILQAYHFTGLSGKLTSRGVCVCISTAFEGNLLDSYFVDLVIQKPLRIHHHSVPVFIPLEEIAAKYLQTNIQHFLFSLCEYLNAYSGRKYQADRLQSDFAALLTGPLQRNPLCNLLSFTYKLDPGGQSFPFCARLLYKDLTATLPTDVTVTCQGVEVLSTSWEEQRASHETLFCTKPLHQVFASFTRKGEKLDMSLVS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CENPO centromere protein O [ Homo sapiens ]
• Official Symbol: CENPO
• Synonyms: CENPO; centromere protein O; CENP O; MGC11266; centromeric protein O; interphase centromere complex protein 36; CENP-O; MCM21R; ICEN-36
• Gene ID: 79172
• mRNA Refseq: NM_001199803
• Protein Refseq: NP_001186732
• MIM: 611504
• UniProt ID: Q9BU64