Recombinant Human CENPO, GST-tagged

• Cat.No.: CENPO-11101H
• Product Overview: Recombinant Human CENPO protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-300a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CENPO centromere protein O [ Homo sapiens ]
• Official Symbol: CENPO
• Synonyms: CENPO; centromere protein O; CENP O; MGC11266; centromeric protein O; interphase centromere complex protein 36; CENP-O; MCM21R; ICEN-36
• Gene ID: 79172
• mRNA Refseq: NM_001199803
• Protein Refseq: NP_001186732
• MIM: 611504
• UniProt ID: Q9BU64
• Chromosome Location: 2p23.3
• Pathway: Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Replication, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; M Phase, organism-specific biosystem; Mitotic M-M/G1 phases, organism-specific biosystem