Recombinant Human CELF3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CELF3-4915H
• Product Overview: CELF3 MS Standard C13 and N15-labeled recombinant protein (NP_009116) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 50.5 kDa
• AA Sequence: MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAKAAINTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQVATQLGMFSPITLQFGAYSAYTQALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAINANGLIATPITPSSGTSTPPAIAATPVSAIPAALGVNGYSQVPTQPTGQPAPDALYPNGVHPYPAQSPAAPVDPLQQAYAGMQHYTAYPAAYSLVAPAFPQPPALVAQQPPPPPQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPYTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CELF3 CUGBP Elav-like family member 3 [ Homo sapiens (human) ]
• Official Symbol: CELF3
• Synonyms: CELF3; CUGBP Elav-like family member 3; CAGH4; ERDA4; ETR-1; TNRC4; BRUNOL1; CUGBP Elav-like family member 3; CAG repeat domain; CAG repeat protein 4; CUG-BP- and ETR-3-like factor 3; ELAV-type RNA-binding protein 1; RNA-binding protein BRUNOL-1; bruno-like protein 1; expanded repeat domain protein CAG/CTG 4; expanded repeat domain, CAG/CTG 4; trinucleotide repeat containing 4; trinucleotide repeat-containing gene 4 protein
• Gene ID: 11189
• mRNA Refseq: NM_007185
• Protein Refseq: NP_009116
• MIM: 612678
• UniProt ID: Q5SZQ8