Recombinant Human CECR1, GST-tagged

• Cat.No.: CECR1-11089H
• Product Overview: Recombinant Human CECR1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 162-511a.a.
• Description: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3 mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CECR1 cat eye syndrome chromosome region, candidate 1 [ Homo sapiens ]
• Official Symbol: CECR1
• Synonyms: CECR1; cat eye syndrome chromosome region, candidate 1; IDGFL; adenosine deaminase CECR1; ADGF; adenosine deaminase 2; cat eye syndrome critical region protein 1; ADA2
• Gene ID: 51816
• mRNA Refseq: NM_017424
• Protein Refseq: NP_059120
• MIM: 607575
• UniProt ID: Q9NZK5
• Chromosome Location: 22q11.2
• Function: adenosine deaminase activity; adenosine receptor binding; growth factor activity; growth factor activity; heparin binding; hydrolase activity; metal ion binding; protein homodimerization activity; proteoglycan binding; zinc ion binding