Recombinant Human CEACAM5 protein, His-tagged

• Cat.No.: CEACAM5-517H
• Product Overview: Recombinant Human CEACAM5 (P06731) fused with His tag was produced in HEK293F cells.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Description: This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
• Form: Freeze-dried powder
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: CEACAM5 carcinoembryonic antigen related cell adhesion molecule 5 [ Homo sapiens (human) ]
• Official Symbol: CEACAM5
• Synonyms: CEACAM5; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; carcinoembryonic antigen-related cell adhesion molecule 5; meconium antigen 100
• Gene ID: 1048
• mRNA Refseq: NM_001291484.2
• Protein Refseq: NP_001278413.1
• UniProt ID: P06731