Active Recombinant Mouse Ceacam5 Protein, Fc-tagged

• Cat.No.: Ceacam5-002M
• Product Overview: Recombinant Mouse CEACAM-5/CD66e (Gln35-Glu947) protein with a Mouse IgG2a (Glu98-Lys330) Fc tag at C-terminus was expressed in Mouse myeloma cell line.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Fc
• Protein Length: 35-947
• Description: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.
• Form: Disulfide-linked homodimer
• Bio-activity: Measured by its binding ability in a functional ELISA. When Recombinant Mouse CEACAM-5/CD66e Fc Chimera is immobilized at 0.5 μg/mL (100 μL/well), Recombinant Mouse Galectin-4 binds with an ED50 of 0.1-0.8 μg/mL.
• Molecular Mass: 130 kDa
• N-terminal Sequence Analysis: Gln35
• Endotoxin: <0.1 EU/μg of the protein by the LAL method.
• Purity: >90% by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 400 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: Ceacam5 carcinoembryonic antigen-related cell adhesion molecule 5 [ Mus musculus (house mouse) ]
• Official Symbol: Ceacam5
• Synonyms: Ceacam5; carcinoembryonic antigen-related cell adhesion molecule 5; Psg; Psg30; 1600029H12Rik; carcinoembryonic antigen-related cell adhesion molecule 5; pregnancy-specific glycoprotein 30
• Gene ID: 73250
• mRNA Refseq: NM_028480
• Protein Refseq: NP_082756
• UniProt ID: Q3UKK2