Recombinant Human CEACAM5 protein, His-Avi-tagged, Biotinylated

• Cat.No.: CEACAM5-840HB
• Product Overview: Biotinylated Recombinant Human CEACAM5/CD66e Protein is expressed from Expi293 with a His and Avi Tag at the C-terminal. It contains Lys35-Ala685.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Lys35-Ala685
• Description: Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 74.2 kDa.Due to glycosylation, the protein migrates to 115-180 KDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.5 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CEACAM5
• Official Symbol: CEACAM5
• Synonyms: CEACAM-5, CD66e, CEA, Meconium antigen 100
• Gene ID: 1048
• mRNA Refseq: NM_001291484.3
• Protein Refseq: NP_001278413.1
• MIM: 114890
• UniProt ID: P06731