Recombinant Human CDKAL1, His-tagged

• Cat.No.: CDKAL1-11058H
• Product Overview: Recombinant Human CDKAL1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-357a.a.
• Description: The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 [ Homo sapiens ]
• Official Symbol: CDKAL1
• Synonyms: CDKAL1; CDK5 regulatory subunit associated protein 1-like 1; threonylcarbamoyladenosine tRNA methylthiotransferase; FLJ20342; tRNA-t(6)A37 methylthiotransferase; FLJ46705; MGC75469
• Gene ID: 54901
• mRNA Refseq: NM_017774
• Protein Refseq: NP_060244
• MIM: 611259
• UniProt ID: Q5VV42
• Chromosome Location: 6p22.2
• Function: 4 iron, 4 sulfur cluster binding; metal ion binding; molecular_function; transferase activity