Recombinant Human CDK5/SNAP25, GST-tagged, Active
Cat.No. : | CDK5/SNAP25-276H |
Product Overview : | Recombinant human full-length CDK5 and p25 were co-expressed by baculovirus inSf9insect cells using an N-terminal GST tag on both proteins. MW=59 kDa and p25 ~49 kDa. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | Sf9 Cells |
Tag : | GST |
Description : | CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction. |
Sequence : | Full-length. |
Applications : | Kinase Assay, Western Blot. |
Storage And Stability : | Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name | CDK5 cyclin-dependent kinase 5 [ Homo sapiens ],SNAP25 synaptosomal-associated protein, 25kDa [ Homo sapiens ] |
Synonyms | CDK5; cyclin-dependent kinase 5; PSSALRE;Cell division protein kinase 5;EC2.7.11.22; Cyclin-dependent kinase 5; Tau protein kinase II catalytic subunit; TPKII catalytic subunit; Serine/threonine-protein kinase; SNAP25; FLJ23079; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SUP; Super-Protein, bA416N4.2; dJ1068F16.2; synapse protein 25,isoform A; CG40452-PA; Snap25-PA; synapse protein 25, isoform B; CG40452-PB; Snap25-PB; OTTHUMP00000030267; OTTHUMP00000030268; Super protein; Synaptosomal-associated 25 kDa protein; resistance to inhibitors of cholinesterase 4 homolog; synaptosomal-associated protein 25; synaptosomal associated protein, 25kDa; Synaptosomal-associated protein, 25kDa; SNAP-25 (synaptosome-associated protein of 25,000 daltons).EF-hand calcium binding protein; FLJ23079 |
Gene ID | 1020,6616 |
mRNA Refseq | NM_001164410,NM_003081 |
Protein Refseq | NP_001157882,NP_003072 |
UniProt ID | Q00535,P60880 |
Chromosome Location | 7q36, 20p12-p11.2 |
MIM | 123831,600322 |
Pathway | Alzheimer"s disease; Axon guidance; Opioid Signalling; SNARE interactions in vesicular transport; Botulinum neurotoxicity; Diabetes pathways; Integration of energy metabolism; Synaptic Transmission |
Function | ATP binding; ErbB-2 class receptor binding; ErbB-3 class receptor binding; acetylcholine receptor activator activity; cyclin-dependent protein kinase activity; nucleotide binding; p53 binding; transferase activity; tau-protein kinase activity;SNAP receptor activity; SNAP receptor activity; soluble NSF attachment protein activity |
◆ Recombinant Proteins | ||
CDK5-4468HF | Active Recombinant Full Length Human CDK5 Protein, DDK-tagged, Biotinylated | +Inquiry |
CDK5-1305R | Recombinant Rat CDK5 Protein | +Inquiry |
CDK5-0879H | Recombinant Human CDK5 protein | +Inquiry |
CDK5-965H | Recombinant Human CDK5 protein, GST-tagged | +Inquiry |
CDK5-27906TH | Recombinant Human CDK5 | +Inquiry |
◆ Cell & Tissue Lysates | ||
CDK5-7626HCL | Recombinant Human CDK5 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Q&As (1)
Ask a question
Is CDK5 derived from human fetal cell lines?
03/28/2023
The CDK5 is expressed from HEK293 host, which is a mammalian cells system.
Ask a Question for All CDK5 Products
Required fields are marked with *
My Review for All CDK5 Products
Required fields are marked with *
0
Inquiry Basket