Recombinant Human CDH3, MYC/DDK-tagged

• Cat.No.: CDH3-289H
• Product Overview: Recombinant Human CDH3 fussed with MYC/DDK tag at C-terminal was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 88.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CDH3 cadherin 3, type 1, P-cadherin (placental) [ Homo sapiens ]
• Official Symbol: CDH3
• Synonyms: CDHP; HJMD; PCAD; cadherin-3; calcium-dependent adhesion protein, placental
• Gene ID: 1001
• mRNA Refseq: NM_001793
• Protein Refseq: NP_001784
• MIM: 114021
• UniProt ID: P22223
• Chromosome Location: 16q22.1
• Pathway: Adherens junctions interactions, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem
• Function: calcium ion binding; molecular_function