Recombinant Human CDCA4 Protein, His-tagged

• Cat.No.: CDCA4-293H
• Product Overview: Recombinant Human CDCA4, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: THis gene encodes a protein that belongs to the E2F family of transcription factors. THis protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulation of JUN oncogene expression. THis protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for tHis gene. Two pseudogenes have also been identified on chromosome 1.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 25.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CDCA4 cell division cycle associated 4 [ Homo sapiens ]
• Official Symbol: CDCA4
• Synonyms: CDCA4; cell division cycle associated 4; cell division cycle-associated protein 4; FLJ20764; hematopoietic progenitor protein; Hepp; HEPP; SEI-3/HEPP; FLJ52878; MGC19517
• Gene ID: 55038
• mRNA Refseq: NM_017955
• Protein Refseq: NP_060425
• MIM: 612270
• UniProt ID: Q9BXL8