Recombinant Human CDC42BPA, GST-tagged, Active

• Cat.No.: CDC42BPA-357H
• Product Overview: Recombinant human MRCKalpha (1-473) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW = 73 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 1-473 a.a.
• Description: Myotonic Dystrophy Kinase-Related Cdc42-Binding Kinase α (MRCKα) is a Cdc42/Rac/Rho interactive/binding serine/threonine kinase with multiple functional domains. MRCK are effectors of RhoA and Cdc42, respectively, for actin reorganization. MRCKα is a critical regulator of signal transduction pathways in eukaryotic cells that are known principally for their role in regulating the cytoskeleton, and they do so by recruiting a variety of downstream effector proteins.
• Sequence: 1-473.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) [ Homo sapiens ]
• Synonyms: CDC42BPA; CDC42 binding protein kinase alpha (DMPK-like); MRCK; MRCKA; PK428; FLJ23347; KIAA0451; DKFZp686L1738; DKFZp686P1738; CDC42-binding protein kinase alpha; ser-thr protein kinase PK428; CDC42 binidng protein kinase beta; CDC42-binding protein kinase alpha (DMPK-like); myotonic dystrophy kinase-related CDC42-binding protein kinase alpha; ser-thr protein kinase related to the myotonic dystrophy protein kinase; EC 2.7.11.1; OTTHUMP00000035727; OTTHUMP00000035728; DMPK-like alpha
• Gene ID: 8476
• mRNA Refseq: NM_003607
• Protein Refseq: NP_003598
• MIM: 603412
• UniProt ID: Q5VT25
• Chromosome Location: 1q42.11
• Function: ATP binding; identical protein binding; magnesium ion binding; nucleotide binding; protein serine/threonine kinase activity; small GTPase regulator activity; transferase activity; zinc ion binding