Recombinant Human CD59 Protein, MYC/DDK-tagged
Cat.No. : | CD59-3116H |
Product Overview : | Recombinant Human CD59 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 11.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name | CD59 CD59 molecule, complement regulatory protein [ Homo sapiens ] |
Official Symbol | CD59 |
Synonyms | 16.3A5; 1F5; EJ16; EJ30; EL32; G344; HRF-20; HRF20; MAC-IP; MACIF; MEM43; MIC11; MIN1; MIN2; |
Gene ID | 966 |
mRNA Refseq | NM_000611 |
Protein Refseq | NP_000602 |
MIM | 107271 |
UniProt ID | P13987 |
◆ Recombinant Proteins | ||
CD59-0836H | Recombinant Human CD59 Protein, GST-Tagged | +Inquiry |
CD59-3116H | Recombinant Human CD59 Protein, MYC/DDK-tagged | +Inquiry |
CD59-1539HFL | Recombinant Full Length Human CD59 Protein, C-Flag-tagged | +Inquiry |
CD59-543H | Recombinant Human CD59 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD59-6833R | Recombinant Rhesus monkey CD59 protein, His & S-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
CD59-1019CCL | Recombinant Cynomolgus CD59 cell lysate | +Inquiry |
CD59-1968HCL | Recombinant Human CD59 cell lysate | +Inquiry |
CD59-1365RCL | Recombinant Rat CD59 cell lysate | +Inquiry |
Not For Human Consumption!
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