Recombinant Human CD58 molecule, His-tagged

• Cat.No.: CD58-682H
• Product Overview: CD58, 29-215aa Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 29-215 a.a.
• Description: CD58 is a member of the immunoglobulin superfamily. This protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. CD58 is localized to the plasma membrane. Alternatively spliced transcript variants have been described. Recombinant human CD58 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. In 20mM Phosphate buffer containing 10% glycerol
• Molecular Mass: 23.8kDa (210aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSFSQQIYG VVYGNVTFHV PSNVPLKEVL WKKQKDKVAE LENSEFRAFS SFKNRVYLDT VSGSLTIYNL TSSDEDEYEM ESPNITDTMK FFLYVLESLP SPTLTCALTN GSIEVQCMIP EHYNSHRGLI MYSWDCPMEQ CKRNSTSIYF KMENDLPQKI QCTLSNPLFN TTSSIILTTC IPSSGHSRHR
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CD58 CD58 molecule [ Homo sapiens ]
• Official Symbol: CD58
• Synonyms: CD58; CD58 molecule; CD58 antigen, (lymphocyte function associated antigen 3) , LFA3; lymphocyte function-associated antigen 3; surface glycoprotein LFA-3; CD58 antigen, (lymphocyte function-associated antigen 3); ag3; LFA3; LFA-3; FLJ23181; FLJ43722
• Gene ID: 965
• mRNA Refseq: NM_001144822
• Protein Refseq: NP_001138294
• MIM: 153420
• UniProt ID: P19256
• Chromosome Location: 1p13
• Pathway: Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem
• Function: protein binding