Recombinant Human CD40L Protein, His/Flag-tagged

• Cat.No.: CD40L-102H
• Product Overview: Human CD40L/CD154 is expressed from mammalian with a His tag and Flag at the N-terminal. It contains M113-L261 Trimer design.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag&His
• Protein Length: M113-L261
• Description: CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Endotoxin: Less than 0.05 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE. > 95% as determined by HPLC.
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CD40LG CD40 ligand [ Homo sapiens (human) ]
• Official Symbol: CD40LG
• Synonyms: IGM; IMD3; TRAP; gp39; CD154; CD40L; HIGM1; T-BAM; TNFSF5; hCD40L
• Gene ID: 959
• mRNA Refseq: NM_000074.3
• Protein Refseq: NP_000065.1
• MIM: 300386
• UniProt ID: P29965