Recombinant Human CD3D&CD3E protein, Fc-Avi-tagged, Biotinylated

• Cat.No.: CD3D&CD3E-234HB
• Product Overview: Biotinylated Human CD3 epsilon & CD3 delta Heterodimer Protein is expressed from mammalian with a Fc and Avi Tag at the C-terminal. It contains Asp 23-Asp 126 (CD3E) & Phe22-Ala105 (CD3D).

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&Fc
• Protein Length: Asp 23-Asp 126 (CD3E) & Phe22-Ala105 (CD3D)
• Description: T-cell surface glycoprotein CD3 epsilon & CD3 delta chain, also known as CD3E & CD3D , are singlepass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a calculated MW of 40 kDa (CD3E) and 35.4 kDa(CD3D).As a result of glycosylation, the protein migrates to 48-60 kDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.05EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: CD3D&CD3E
• Official Symbol: CD3D&CD3E
• Synonyms: CD3; CD3D; CD3-DELTA; T3D; CD3E
• Gene ID: 915 & 916
• mRNA Refseq: NM_000732.6 & NM_000733.4
• Protein Refseq: NP_000723.1 & NP_000724.1
• MIM: 186790 & 186830
• UniProt ID: P04234 & P07766