Recombinant Human CD2AP Protein, His-tagged

• Cat.No.: CD2AP-151H
• Product Overview: Recombinant Human CD2 associated protein(CD2AP)(NM_012120), with a His tag, was expressed in human cells.

Specification

• Species: Human
• Source: Human Cells
• Tag: His
• Description: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.159, without any preservatives.
• Molecular Mass: 71.3 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: CD2AP CD2-associated protein [ Homo sapiens ]
• Official Symbol: CD2AP
• Synonyms: CD2AP; CD2-associated protein; CMS; adapter protein CMS; cas ligand with multiple SH3 domains; Cas ligand with multiple Src homology 3 (SH3) domains; DKFZp586H0519
• Gene ID: 23607
• mRNA Refseq: NM_012120
• Protein Refseq: NP_036252
• MIM: 604241
• UniProt ID: Q9Y5K6