Recombinant Human CD2AP Protein, MYC/DDK-tagged

• Cat.No.: CD2AP-3053H
• Product Overview: Recombinant Human CD2AP protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 71.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CD2AP CD2-associated protein [ Homo sapiens ]
• Official Symbol: CD2AP
• Synonyms: CMS
• Gene ID: 23607
• mRNA Refseq: NM_012120
• Protein Refseq: NP_036252
• MIM: 604241
• UniProt ID: Q9Y5K6