Recombinant Human CD1C Protein, Fc-tagged

• Cat.No.: CD1C-827H
• Product Overview: Recombinant Human CD1C(Asn18-Met302) fused with Fc tag at C-terminal was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 18-302 a.a.
• Description: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
• Form: 1 x PBS, pH7.4, 10% glycerol.
• Molecular Mass: 59 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CD1C CD1c molecule [ Homo sapiens ]
• Official Symbol: CD1C
• Synonyms: CD1C; CD1c molecule; CD1, CD1c antigen , CD1C antigen, c polypeptide; T-cell surface glycoprotein CD1c; CD1C antigen, c polypeptide; cortical thymocyte antigen CD1C; differentiation antigen CD1-alpha-3; R7; CD1; CD1A; BDCA1
• Gene ID: 911
• mRNA Refseq: NM_001765
• Protein Refseq: NP_001756
• MIM: 188340
• UniProt ID: P29017