Recombinant Human CD163 Protein, Ser42-Ser1045, C-His-Avi tagged, Biotinylated

• Cat.No.: CD163-034H
• Product Overview: Recombinant human CD163-C-His-Avi protein was developed from HEK293 and has a target region of C-His-Avi.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Ser42-Ser1045
• Description: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Conjugation/Label: Biotin
• Form: Lyophilised
• Endotoxin: Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg).
• Notes: FOR RESEARCH USE ONLY (RUO).
• Storage: The lyophilized protein is stable for at least 1 year from date of receipt at -20 centigrade.
• Storage Buffer: Lyophilised from 0.2 μm filtered PBS solution pH 7.4. Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20 sec, 5K RPM

Gene Information

• Gene Name: CD163 CD163 molecule [ Homo sapiens (human) ]
• Official Symbol: CD163
• Synonyms: CD163; CD163 molecule; CD163 antigen; scavenger receptor cysteine-rich type 1 protein M130; M130; MM130; hemoglobin scavenger receptor; macrophage-associated antigen
• Gene ID: 9332
• mRNA Refseq: NM_004244
• Protein Refseq: NP_004235
• MIM: 605545
• UniProt ID: Q86VB7