Recombinant Human CCL5 Protein
Cat.No. : | CCL5-43H |
Product Overview : | Recombinant Human CCL5 Protein was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Protein Length : | 67 amino acid |
Description : | Human CCL5, also known as Regulated upon Activation, Normal T cell Expressed and presumably Secreted (RANTES), attracts and activates leukocytes and plays a primary role in the inflammatory immune response. CCL5 activates several G protein-coupled receptors including CCRs 1, 3, 4, and 5. CCL5 binding to CCR5 inhibits the infectivity of M-tropic HIV-1 strains. Proteolytic removal of the two N-terminal residues by CD26 generates a CCL5 variant that functions as a more potent HIV-1 inhibitor and a CCR5 antagonist. |
Form : | Lyophilized |
Molecular Mass : | 7.84701 kDa |
AA Sequence : | SPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQ VCANPEKKWVREYINSLEMS |
Endotoxin : | Endotoxin-free <0.01 EU/ug |
Purity : | Purity assessed by HPLC, Mass Spectrometry, and NMR |
Storage : | Store at -20 to -80 centigrade for 12 months; Store at 4 centigrade for 6 months; Store at RT for 1 month. |
tmpcolum67 : | C-C motif chemokine ligand 5 |
Gene Name | CCL5 C-C motif chemokine ligand 5 [ Homo sapiens (human) ] |
Official Symbol | CCL5 |
Synonyms | SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta |
Gene ID | 6352 |
mRNA Refseq | NM_002985 |
Protein Refseq | NP_002976 |
MIM | 187011 |
UniProt ID | P13501 |
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Not For Human Consumption!
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