Recombinant Human CCL11 Protein, DYKDDDDK-tagged

• Cat.No.: CCL11-213H
• Product Overview: Recombinant Human C-C motif chemokine ligand 11(CCL11)(NM_002986), with a DYKDDDDK tag, was expressed in human cells.

Specification

• Species: Human
• Source: Human Cells
• Tag: Flag
• Description: This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.97, without any preservatives.
• Molecular Mass: 8.56kD
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: CCL11 chemokine (C-C motif) ligand 11 [ Homo sapiens ]
• Official Symbol: CCL11
• Synonyms: CCL11; chemokine (C-C motif) ligand 11; SCYA11, small inducible cytokine subfamily A (Cys Cys), member 11 (eotaxin); eotaxin; eotaxin 1; MGC22554; eotaxin-1; C-C motif chemokine 11; small-inducible cytokine A11; eosinophil chemotactic protein; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); SCYA11
• Gene ID: 6356
• mRNA Refseq: NM_002986
• Protein Refseq: NP_002977
• MIM: 601156
• UniProt ID: P51671