Recombinant Human CCL11 Protein

• Cat.No.: CCL11-08H
• Product Overview: Recombinant Human CCL11 Protein without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: Eotaxin, also known as Eotaxin-1 and CCL11, is a chemokine that recruits eosinophils to sites of allergic inflammation. Eotaxin signals through the G protein-coupled chemokine receptors CCR2, CCR3, and CCR5. Eotaxin also negatively regulates adult neurogenesis, and high Eotaxin levels are associated with impaired learning and memory.
• Bio-activity: No biological activity data is available at this time.
• Molecular Mass: Monomer, 8.4 kDa (74 aa)
• AA Sequence: GPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP
• Endotoxin: ≤1 EUs/μg, Kinetic LAL
• Purity: ≥95%, Reducing and Non-Reducing SDS PAGE
• Stability: 12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
  1 month when stored at 4 centigrade after reconstituting as directed.
  3 months when stored at -20 to -80 centigrade after reconstituting as directed.
• Storage: Storage Prior to Reconstitution: -20 centigrade
• Storage Buffer: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
• Reconstitution: Sterile water at 0.1 mg/mL
• Shipping: Room temperature
• Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.

Gene Information

• Gene Name: CCL11 chemokine (C-C motif) ligand 11 [ Homo sapiens (human) ]
• Official Symbol: CCL11
• Synonyms: CCL11; chemokine (C-C motif) ligand 11; SCYA11, small inducible cytokine subfamily A (Cys Cys), member 11 (eotaxin); eotaxin; eotaxin 1; MGC22554; eotaxin-1; C-C motif chemokine 11; small-inducible cytokine A11; eosinophil chemotactic protein; small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin); SCYA11
• Gene ID: 6356
• mRNA Refseq: NM_002986
• Protein Refseq: NP_002977
• MIM: 601156
• UniProt ID: P51671