Recombinant Human CCDC93, GST-tagged

• Cat.No.: CCDC93-10825H
• Product Overview: Recombinant Human CCDC93 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: C-term-350a.a.
• Description: The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CCDC93 coiled-coil domain containing 93 [ Homo sapiens ]
• Official Symbol: CCDC93
• Synonyms: CCDC93; coiled-coil domain containing 93; coiled-coil domain-containing protein 93; FLJ10996; FLJ25197; MGC13033
• Gene ID: 54520
• mRNA Refseq: NM_019044
• Protein Refseq: NP_061917
• UniProt ID: Q567U6
• Chromosome Location: 2q14.1