Recombinant Human CBX4, GST-tagged

• Cat.No.: CBX4-10769H
• Product Overview: Recombinant Human CBX4 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene may be involved in the transitioning of erythroblasts from a highly proliferative state to a terminal phase of differentiation. High level expression of the encoded protein can lead to apoptosis. Several transcript variants encoding different isoforms have been found for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-290a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CBX4 chromobox homolog 4 [ Homo sapiens ]
• Official Symbol: CBX4
• Synonyms: CBX4; chromobox homolog 4; chromobox homolog 4 (Drosophila Pc class); E3 SUMO-protein ligase CBX4; hPC2; NBP16; NS5ATP1 binding protein 16; Pc class 2 homolog (Drosophila); PC2; Pc class 2 homolog; polycomb 2 homolog; NS5ATP1-binding protein 16; chromobox protein homolog 4; chromobox homolog 4 (Pc class homolog, Drosophila)
• Gene ID: 8535
• mRNA Refseq: NM_003655
• Protein Refseq: NP_003646
• MIM: 603079
• UniProt ID: O00257
• Chromosome Location: 17q25.3
• Pathway: C-MYB transcription factor network, organism-specific biosystem; Regulation of retinoblastoma protein, organism-specific biosystem
• Function: chromatin binding; enzyme binding; methylated histone residue binding; phosphoprotein binding; protein binding; single-stranded RNA binding; transcription corepressor activity