Recombinant Human Cathepsin L2, His-tagged

• Cat.No.: CTSL2-507H
• Product Overview: Recombinant Human cathepsin V, CD33 signal peptide(1-16aa) + cathepsin V (a-a 18-334), with C-terminal His tag expressed inFreeStyle 293-F cells. MW= 37 kDa.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 1-16;18-334 a.a.
• Description: The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes.
• Purity: >90%.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20 and 10% glycerol.
• Stability: >6 months at –80°C.

Gene Information

• Gene Name: CTSL2 cathepsin L2 [ Homo sapiens ]
• Synonyms: CTSL2; cathepsin L2; CTSU; CTSV; CATL2; MGC125957;EC3.4.22.43; Cathepsin L2; Cathepsin V; Cathepsin U; UNQ268/PRO305
• Gene ID: 1515
• mRNA Refseq: NM_001333
• Protein Refseq: NP_001324
• MIM: 603308
• UniProt ID: O60911
• Chromosome Location: 9q22.2
• Pathway: Lysosome
• Function: cysteine-type endopeptidase activity; peptidase activity; protein binding