Recombinant Human CARD11 Protein, Myc/DDK-tagged
Cat.No. : | CARD11-01H |
Product Overview : | Purified recombinant protein of Homo sapiens caspase recruitment domain family, member 11 (CARD11) with a C-Myc/DDK tag was expressed in HEK293T. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. |
Molecular Mass : | 133.1 kDa |
AA Sequence : | MPGGGPEMDDYMETLKDEEDALWENVECNRHMLSRYINPAKLTPYLRQCKVIDEQDEDEVLNAPMLPSKINRAGRLLDILHTKGQRGYVVFLESLEFYYPELYKLVTGKEPTRRFSTIVVEEGHEGLTHFLMNEVIKLQQQMKAKDLQRCELLARLRQLEDEKKQMTLTRVELLTFQERYYKMKEERDSYNDELVKVKDDNYNLAMRYAQLSEEKNMAVMRSRDLQLEIDQLKHRLNKMEEECKLERNQSLKLKNDIENRPKKEQVLELERENEMLKTKNQELQSIIQAGKRSLPDSDKAILDILEHDRKEALEDRQELVNRIYNLQEEARQAEELRDKYLEEKEDLELKCSTLGKDCEMYKHRMNTVMLQLEEVERERDQAFHSRDEAQTQYSQCLIEKDKYRKQIRELEEKNDEMRIEMVRREACIVNLESKLRRLSKDSNNLDQSLPRNLPVTIISQDFGDASPRTNGQEADDSSTSEESPEDSKYFLPYHPPQRRMNLKGIQLQRAKSPISLKRTSDFQAKGHEEEGTDASPSSCGSLPITNSFTKMQPPRSRSSIMSITAEPPGNDSIVRRYKEDAPHRSTVEEDNDSGGFDALDLDDDSHERYSFGPSSIHSSSSSHQSEGLDAYDLEQVNLMFRKFSLERPFRPSVTSVGHVRGPGPSVQHTTLNGDSLTSQLTLLGGNARGSFVHSVKPGSLAEKAGLREGHQLLLLEGCIRGERQSVPLDTCTKEEAHWTIQRCSGPVTLHYKVNHEGYRKLVKDMEDGLITSGDSFYIRLNLNISSQLDACTMSLKCDDVVHVRDTMYQDRHEWLCARVDPFTDHDLDMGTIPSYSRAQQLLLVKLQRLMHRGSREEVDGTHHTLRALRNTLQPEEALSTSDPRVSPRLSRASFLFGQLLQFVSRSENKYKRMNSNERVRIISGSPLGSLARSSLDATKLLTEKQEELDPESELGKNLSLIPYSLVRAFYCERRRPVLFTPTVLAKTLVQRLLNSGGAMEFTICKSDIVTRDEFLRRQKTETIIYSREKNPNAFECIAPANIEAVAAKNKHCLLEAGIGCTRDLIKSNIYPIVLFIRVCEKNIKRFRKLLPRPETEEEFLRVCRLKEKELEALPCLYATVEPDMWGSVEELLRVVKDKIGEEQRKTIWVDEDQLSGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol |
Gene Name | CARD11 caspase recruitment domain family member 11 [ Homo sapiens (human) ] |
Official Symbol | CARD11 caspase recruitment domain family member 11 [ Homo sapiens (human) ] |
Synonyms | CARD11; caspase recruitment domain family member 11; PPBL; BENTA; BIMP3; IMD11; CARMA1; IMD11A; caspase recruitment domain-containing protein 11; CARD-containing MAGUK protein 1; bcl10-interacting maguk protein 3; carma 1 |
Gene ID | 84433 |
mRNA Refseq | NM_032415 |
Protein Refseq | NP_115791 |
MIM | 607210 |
UniProt ID | Q9BXL7 |
◆ Recombinant Proteins | ||
CARD11-1312C | Recombinant Chicken CARD11 | +Inquiry |
CARD11-0391H | Recombinant Human CARD11 Protein, GST-Tagged | +Inquiry |
CARD11-01H | Recombinant Human CARD11 Protein, Myc/DDK-tagged | +Inquiry |
CARD11-2728M | Recombinant Mouse CARD11 Protein | +Inquiry |
CARD11-301642H | Recombinant Human CARD11 protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
CARD11-7850HCL | Recombinant Human CARD11 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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