Recombinant Human CAPN7 Protein (Met1-Pro157), N-His tagged

• Cat.No.: CAPN7-0814H
• Product Overview: Recombinant Human CAPN7 (Met1-Pro157) fused with the N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Met1-Pro157
• Description: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 20.13 kDa
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles.
  Store at 2 to 8 centigrade for one week.
  Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02% NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: CAPN7 calpain 7 [ Homo sapiens (human) ]
• Official Symbol: CAPN7
• Synonyms: CAPN7; calpain 7; PALBH; CALPAIN7; calpain-7; calpain like protease; homolog of Aspergillus Nidulans PALB; palB homolog
• Gene ID: 23473
• mRNA Refseq: NM_014296
• Protein Refseq: NP_055111
• MIM: 606400
• UniProt ID: Q9Y6W3