CAPN7
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Official Full Name
calpain 7 -
Overview
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008] -
Synonyms
CAPN7;calpain 7;PALBH;CALPAIN7;calpain-7;palB homolog;calpain like protease;homolog of Aspergillus Nidulans PALB
Recombinant Proteins
- Mouse
- Human
- Zebrafish
- Mammalian Cell
- HEK293
- E.coli
- Wheat Germ
- HEK293T
- His
- Myc&DDK
- GST
- Non
- His&Fc&Avi
- His&T7
Involved Pathway
CAPN7 involved in several pathways and played different roles in them. We selected most pathways CAPN7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CAPN7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CAPN7 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CAPN7 itself. We selected most functions CAPN7 had, and list some proteins which have the same functions with CAPN7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
CAPN7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAPN7 here. Most of them are supplied by our site. Hope this information will be useful for your research of CAPN7.
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References
- Sonati, T; Reimann, RR; et al. The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. NATURE 501:102-+(2013).
- Zhang, ZQ; Zoltewicz, JS; et al. Human Traumatic Brain Injury Induces Autoantibody Response against Glial Fibrillary Acidic Protein and Its Breakdown Products. PLOS ONE 9:-(2014).
