Recombinant Human CANX Protein, His-tagged

• Cat.No.: CANX-207H
• Product Overview: Recombinant Human CANX(His21-Pro481), transcript variant 2, fused with His tag at N-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: His21-Pro481
• Description: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
• Form: 20mM Tris-HCl, 150mM NaCl, 2mM CaCl, 10% Glycerol, pH 7.5.
• Molecular Mass: 53.5 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Storage: Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CANX calnexin [ Homo sapiens ]
• Official Symbol: CANX
• Synonyms: CANX; calnexin; CNX; IP90; major histocompatibility complex class I antigen binding protein p88; P90; major histocompatibility complex class I antigen-binding protein p88; FLJ26570
• Gene ID: 821
• mRNA Refseq: NM_001024649
• Protein Refseq: NP_001019820
• MIM: 114217
• UniProt ID: P27824