Recombinant Human CANX, GST-tagged

• Cat.No.: CANX-10695H
• Product Overview: Recombinant Human CANX protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-273a.a.
• Description: This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CANX calnexin [ Homo sapiens ]
• Official Symbol: CANX
• Synonyms: CANX; calnexin; CNX; IP90; major histocompatibility complex class I antigen binding protein p88; P90; major histocompatibility complex class I antigen-binding protein p88; FLJ26570
• Gene ID: 821
• mRNA Refseq: NM_001024649
• Protein Refseq: NP_001019820
• MIM: 114217
• UniProt ID: P27824
• Chromosome Location: 5q35
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Asparagine N-linked glycosylation, organism-specific biosystem; Assembly of Viral Components at the Budding Site, organism-specific biosystem; Calnexin/calreticulin cycle, organism-specific biosystem
• Function: calcium ion binding; protein binding; sugar binding; unfolded protein binding