Recombinant Human Calnexin

• Cat.No.: CANX-1394H
• Product Overview: Recombinant Human Calnexin protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 52.5 kDa (462aa).

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Calnexin, also known as IP90, p88 and p90, is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
• Amino Acid Sequence: MHDGHDDDVI DIEDDLDDVI EEVEDSKPDT TAPPSSPKVT YKAPVPTGEV YFADSFDRGT LSGWILSKAK KDDTDDEIAK YDGKWEVEEM KESKLPGDKG LVLMSRAKHH AISAKLNKPF LFDTKPLIVQ YEVNFQNGIE CGGAYVKLLS KTPELNLDQF HDKTPYTIMF GPDKCGEDYK LHFIFRHKNP KTGIYEEKHA KRPDADLKTY FTDKKTHLYT LILNPDNSFE ILVDQSVVNS GNLLNDMTPP VNPSREIEDP EDRKPEDWDE RPKIPDPEAV KPDDWDEDAP AKIPDEEATK PEGWLDDEPE YVPDPDAEKP EDWDEDMDGE WEAPQIANPR CESAPGCGVW QRPVIDNPNY KGKWKPPMID NPSYQGIWKP RKIPNPDFFE DLEPFRMTPF SAIGLELWSM TSDIFFDNFI ICADRRIVDD WANDGWGLKK AADGAAEPGV VGQMIEAAEE RP
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT and 20% glycerol.
• Purity: > 90% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CANX calnexin [ Homo sapiens ]
• Synonyms: CANX; calnexin; CNX; P90; IP90; FLJ26570; major histocompatibility complex class I antigen-binding protein p88
• Gene ID: 821
• mRNA Refseq: NM_001024649
• Protein Refseq: NP_001019820
• MIM: 114217
• UniProt ID: P27824
• Chromosome Location: 5q35
• Pathway: Antigen processing and presentation
• Function: calcium ion binding; sugar binding; unfolded protein binding