Recombinant Human Cancer/testis Antigen 1B, GST-tagged

• Cat.No.: CTAG1B-4480H
• Product Overview: NY-ESO-1 Human Recombinant full length protein expressed in E.coli, shows a 49 kDa SDS-PAGE (including GST tag). The NY-ESO-1 is purified by proprietary chromatographic techniques.

Specification

• Species: Human
• Source: Human
• Tag: GST
• Description: NY-ESO-1, a member of the CT (cancer/testis) family, is a tumor-specific shared antigen with distinctive immunogenicity. NY-ESO-1 is expressed in testis and ovary and in a wide variety of cancers. It is also detected in uterine myometrium. The expression is from 18 weeks until birth in human fetal testis. Furthermore, in the adult testis, NY-ESO-1 is strongly expressed in spermatogonia and in primary spermatocytes, but not in post-meiotic cells or in testicular somatic cells (at protein level). The molecular basis of T cell-mediated antitumor immunity has been elucidated by the identification of a number of tumor antigens recognized by CD8+ T cells. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen.
• Form: NY-ESO-1 at 100µg/ml in 50mM Tris-Acetate, pH7.5, 1mM EDTA and 20% Glycerol.
• Physical Appearance: Sterile Filtered clear solution.
• Storage: Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.
• Full Length: Full L.

Gene Information

• Gene Name: CTAG1B cancer/testis antigen 1B [ Homo sapiens ]
• Official Symbol: CTAG1B
• Synonyms: CTAG1B; cancer/testis antigen 1B; CTAG; ESO1; CT6.1; CTAG1; LAGE-2; LAGE2B; NY-ESO-1; cancer antigen 3; New York esophageal squamous cell carcinoma 1; LAGE2A; Cancer/testis antigen 1; L antigen family member 2; Autoimmunogenic cancer/testis antigen NY-ESO-1; Cancer/testis antigen 6.1
• Gene ID: 1485
• mRNA Refseq: NM_001327
• Protein Refseq: NP_001318
• MIM: 300156
• UniProt ID: P78358
• Chromosome Location: Xq28