Recombinant Human CAMK4, GST-tagged, Active

• Cat.No.: CAMK4-268H
• Product Overview: Recombinant full-length human CAMK4 was expressed by baculovirus inSf9insect cells using a N-terminal GST tag. MW = 79 kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: CAMK4 is a multifunctional serine/threonine protein kinase and a member of Ca(2+)/calmodulin- dependent protein kinase family. CAMK4 is localized in neurons in the hippocampus, amygdala, anterior cingulate cortex, somatosensory cortex, and insular cortex. CAMK4 is involved in neural activity-dependent signaling in the neuronal nucleus and thought to plays an important role in the consolidation/retention of hippocampus-dependent long-term memory.
• Sequence: Full-length.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: CAMK4 calcium/calmodulin-dependent protein kinase IV [ Homo sapiens ]
• Synonyms: CAMK4; calcium/calmodulin-dependent protein kinase IV; CaMK-GR; MGC36771; CAM kinase IV; CAM kinase- GR; brain Ca++-calmodulin-dependent protein kinase type IV; brain Ca(2+)-calmodulin-dependent protein kinase type IV; calcium/calmodulin-dependent protein kinase type IV catalytic chain; EC 2.7.11.17; CaMK IV
• Gene ID: 814
• mRNA Refseq: NM_001744
• Protein Refseq: NP_001735
• MIM: 114080
• UniProt ID: Q16566
• Chromosome Location: 5q21.3
• Pathway: Calcium signaling pathway; Long-term potentiation; Neurotrophin signaling pathway
• Function: ATP binding; calcium ion binding; calmodulin binding; calmodulin-dependent protein kinase activity; nucleotide binding; transcription activator activity; transferase activity