Recombinant Human CAMK2A, His-tagged

• Cat.No.: CAMK2A-1186H
• Product Overview: Recombinant humanfull length CAMK2A with His tag is expressed ininsect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Description: CAMK2A is an enzyme thatin humans is encoded by the CAMK2A gene.The product of this gene belongs tothe Serine/Threonine protein kinases family, and to the Ca2+/calmodulin-dependentprotein kinases subfamily. Calcium signaling is crucial for several aspectsof plasticity at glutamatergic synapses. This enzyme is composed of fourdifferent chains: alpha, beta, gamma, and delta. The alpha chain encoded bythis gene is required for hippocampal long-term potentiation (LTP) andspatial learning.
• Form: Liquid in20 mM Tris, pH 7.5 + 100 mM NaCl + 0.5 mM EDTA + 0.05% NP-40 + 2 Mm DTT + 50%glycerol.
• Molecular Weight: 56.8 kDa
• Concentration: 0.34 mg/ml
• Purity: ≥90%
• Specific Activity: 7300nmole of phosphate transferred to autocamtide-2 per minute per mg of totalprotein at 30°C. Activity determined at a final protein concentration of 0.05ug/ml.
• Storage: Stable for 6 monthsin working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: CAMK2A
• Full Length: Full L.

Gene Information

• Gene Name: CAMK2Acalcium/calmodulin-dependent protein kinase II alpha [ Homo sapiens ]
• Synonyms: CAMK2A;calcium/calmodulin-dependent protein kinase II alpha; CAMKA; KIAA0968;CaMKIIN alpha; CaMK-II alpha subunit; CaM-kinase II alpha chain; CaM kinaseII alpha subunit; calcium/calmodulin-dependent protein kinase II alpha-Bsubunit; calcium/calmodulin-dependent protein kinase type II alpha chain;calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha; EC2.7.11.17; OTTHUMP00000165787; OTTHUMP00000165788; CaM kinase II subunitalpha; CaMK-II subunit alpha
• Gene ID: 815
• mRNA Refseq: NM_015981
• Protein Refseq: NP_057065
• MIM: 114078
• UniProt ID: Q9UQM7
• Chromosome Location: 5q32
• Pathway: Calcium signaling pathway; ErbBsignaling pathway; Glioma; GnRH signaling pathway; Long-term potentiation;Melanogenesis; Neurotrophin signaling pathway; Olfactory transduction; Wntsignaling pathway
• Function: ATP binding; calmodulinbinding; calmodulin-dependent protein kinase activity; nucleotide binding;transferase activity