Recombinant Human calponin 2, His-tagged

• Cat.No.: CNN2-482H
• Product Overview: CNN2, 1-131aa Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-131 a.a.
• Description: CNN2 protein, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. This protein could play a role in smooth muscle contraction and cell adhesion. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human CNN2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol.
• Molecular Mass: 16.9 kDa (154aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSSTQFN KGPSYGLSAE VKNRLLSKYD PQKEAELRTW IEGLTGLSIG PDFQKGLKDG TILCTLMNKL QPGSVPKINR SMQNWHQLEN LSNFIKAMVS YGMNPVDLFE ANDLFESGNM TQVQVSLLAL AGKA
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CNN2 calponin 2 [ Homo sapiens ]
• Official Symbol: CNN2
• Synonyms: CNN2; calponin 2; calponin-2; neutral calponin; calponin H2, smooth muscle
• Gene ID: 1265
• mRNA Refseq: NM_004368
• Protein Refseq: NP_004359
• MIM: 602373
• UniProt ID: Q99439
• Chromosome Location: 19p13.3
• Pathway: Myometrial Relaxation and Contraction Pathways, organism-specific biosystem
• Function: actin binding; calmodulin binding