Recombinant Human Calponin 1, Basic, Smooth Muscle, His-tagged

• Cat.No.: CNN1-6836H
• Product Overview: Recombinant human CNN1 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-297aa
• Description: CNN1 belongs to the calponin family. CNN1 is thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.15M NaCl, 1mM DTT.
• Molecular Mass: 34.2 kDa (305aa) confirmed by MALDI-TOF
• AA Sequence: MSSAHFNRGP AYGLSAEVKN KLAQKYDHQR EQELREWIEG VTGRRIGNNF MDGLKDGIIL CEFINKLQPG SVKKINESTQ NWHQLENIGN FIKAITKYGV KPHDIFEAND LFENTNHTQV QSTLLALASM AKTKGNKVNV GVKYAEKQER KFEPGKLREG RNIIGLQMGT NKFASQQGMT AYGTRRHLYD PKLGTDQPLD QATISLQMGT NKGASQAGMT APGTKRQIFE PGLGMEHCDT LNVSLQMGSN KGASQRGMTV YGLPRQVYDP KYCLTPEYPE LGEPAHNHHA HNYYNSALEH HHHHH
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: CNN1 calponin 1, basic, smooth muscle [ Homo sapiens ]
• Official Symbol: CNN1
• Synonyms: CNN1; calponin 1, basic, smooth muscle; calponin-1; Sm Calp; SMCC; basic calponin; calponins, basic; calponin H1, smooth muscle; Sm-Calp
• Gene ID: 1264
• mRNA Refseq: NM_001299
• Protein Refseq: NP_001290
• MIM: 600806
• UniProt ID: P51911
• Chromosome Location: 19p13.2-p13.1
• Pathway: Myometrial Relaxation and Contraction Pathways, organism-specific biosystem
• Function: actin binding; calmodulin binding