Recombinant Human CALN1, His-tagged

• Cat.No.: CALN1-2869H
• Product Overview: Recombinant human CALN1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: CALN1 is high similarity to the calcium-binding proteins of the calmodulin family. This protein contains two EF-hand domains and potential calcium-binding sites. Also, Itnegatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CALN1 play a role in the physiology of neurons and is potentially important in memory and learning.
• Sequence: MGSSHHHHHH SSGLVPRGSH MPFHHVTAGL LYKGNYLNRS LSAGSDSEQL ANISVEELDE IREAFRVLDR DGNGFISKQE LGMAMRSLGY MPSEVELAII MQRLDMDGDG QVDFDEFMTI LGPKLVSSEG RDGFLGNTID SIFWQFDMQR ITLEELKHIL YHAFRDHLTM KDIENIIINE EESLNETSGN CQTEFEGVHS QKQNRQTCVR KS.
• Purity: > 90% by SDS – PAGE.
• MW: 24.0 kDa (212aa) confirmed by MALDI-TOF.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 50mM NaCl, 0.1mM PMSF.
• Concentration: 0.5mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CALN1 calneuron 1 [ Homo sapiens ]
• Synonyms: CALN1; calneuron 1; OTTHUMP00000160216; OTTHUMP00000198477; OTTHUMP00000198493; OTTHUMP00000210382; OTTHUMP00000210383; calcium-binding protein 8; calcium-binding protein CABP8; calneuron I; calneuron-; CABP8; CALN1
• Gene ID: 83698
• mRNA Refseq: NM_001017440
• Protein Refseq: NP_001017440
• MIM: 607176
• UniProt ID: Q9BXU9
• Chromosome Location: 7q11
• Function: calcium ion binding