Recombinant Human CALD1 Protein, MYC/DDK-tagged

• Cat.No.: CALD1-2290H
• Product Overview: Recombinant human CALD1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293

Specification

• Description: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 65.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: CALD1 caldesmon 1 [ Homo sapiens ]
• Official Symbol: CALD1
• Synonyms: CDM; H-CAD; HCAD; L-CAD; LCAD; NAG22
• Gene ID: 800
• mRNA Refseq: NM_033138
• Protein Refseq: NP_149129
• MIM: 114213
• UniProt ID: Q05682