Recombinant Human Calcium Binding Protein 39, His-tagged

• Cat.No.: CAB39-2721H
• Product Overview: Recombinant human CAB39, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW =42 kDa (361aa), confirmed by MALDI-TOF.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Calcium binding protein 39, also known as CAB39, is a 40-kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. Also CAB39 may function as a scaffolding component of the STK11/STRAD complex and regulates STK11 activity and cellular localization.
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MPFPFGKSHK SPADIVKNLK ESMAVLEKQD ISDKKAEKAT EEVSKNLVAM KEILYGTNEK EPQTEAVAQL AQELYNSGLL STLVADLQLI DFEGKKDVAQ IFNNILRRQI GTRTPTVEYI CTQQNILFML LKGYESPEIA LNCGIMLREC IRHEPLAKII LWSEQFYDFF RYVEMSTFDI ASDAFATFKD LLTRHKLLSA EFLEQHYDRF FSEYEKLLHS ENYVTKRQSL KLLGELLLDR HNFTIMTKYI SKPENLKLMM NLLRDKSRNI QFEAFHVFKV FVANPNKTQP ILDILLKNQA KLIEFLSKFQ NDRTEDEQFN DEKTYLVKQI RDLKRPAQQE A
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol.
• Purity: > 90% by SDS – PAGE.
• Concentration: 1mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CAB39 calcium binding protein 39 [ Homo sapiens ]
• Synonyms: CAB39; calcium binding protein 39; MO25; CGI-66; FLJ22682; Protein Mo25
• Gene ID: 51719
• mRNA Refseq: NM_001130849
• Protein Refseq: NP_001124321
• MIM: 612174
• UniProt ID: Q9Y376
• Chromosome Location: 2q37.1
• Pathway: mTOR signaling pathway; Integration of energy metabolism
• Function: protein binding